University of Illinois at Urbana-Champaign
  PepShop is an unified web-portal of neuropeptide and prohormone (or proprotein) information. Sequence and mass spectra data is integrated from cleavage prediction and other bionformatics tools mainly from NeuroPred and SwePep with information and tools from UniProt, NCBI.
Accession Number
Prohormone Symbol
Monoisotopic mass (in Daltons)    Mass tolerance (±)    
Prohormone sequence

MS/MS spectrum search  X!Tandem  Crux  OMSSA

Predict Fragment Ions from Sequence
    Please paste sequence in submission box
Precursor charge state
Mass type  monoisotopic  average
Ion types  a ions  b ions  c ions  x ions  y ions  z ions
Neutral mass losses
 Ammonia loss (-17Da)  Water loss (-18Da)

Please submit sequence in fasta format
or upload file            

NeuroPred Parameters
Model Selection
Trim C-terminal K and R
Most Common PTMs
Less Common PTMs
Amidation O-linked Glycosylation of S N-linked Glycosylation of S Bromination of W
Pyroglutamination O-linked Glycosylation of T N-linked Glycosylation of T Methylation of E
Acetylation Dipeptidase Hydroxylation of P Methylation of H
Sulfation of Y Carboxylation of E Phosphorylation of S Methylation of K
  DiAcetylation Phosphorylation of T Methylation of R

BLAST Parameters
Database Selection

Questions or comments: Sandra Rodriguez Zas (
NIDA Logo  This Database is supported by NIH/NIDA Grants: R21 DA027548
 and P30 DA 018310.
  NIH Logo